The Association Between Age Groups with Clinicopathologic and Molecular Subtypes of Breast Cancer Patients

نویسندگان

چکیده

<p align="center"> </p><p><strong>Introduction:</strong> The increase in incidence proportion of breast cancer disease among young patients < 40 years old is exceeding that older patients. purpose the research to know differences between clinicopathologic and molecular subtypes ≥ old.</p><p><strong>Methods:</strong> conducting on Medical Records (MR) was an observational analytic method with a cross-sectional design. independent variable age. Dependent variables were histopathological type, stage disease, grade tumor, subtype cancer. Univariate analyses describe samples. those according age groups analyzed by bivariate statistic odds ratio confident interval (CI) 95% each would be displayed binary logistic regression statistic. </p><p><strong>Results: </strong>The most prevalent range 50-59 (47%), mean 53.66 ± 0.977 years, 29 86 old, aged 12%. Ductal carcinoma type (89.7%), III tumor (40.2%), poor differentiation (60.7%), luminal A (42.7%) subtypes. There weren’t histopathologic different from (p=0.015). Old had worse than (OR 2.166; CI 0.973-4.823).</p><strong>Conclusions:</strong> significant groups. poorer years. </p>

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region

چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...

15 صفحه اول

The association between CD166 detection rate and clinicopathologic parameters of Patients with colorectal cancer

Background: Metastasis and recurrence of colorectal cancer after treatment is attributed to stem cells. The aim of this study was to determine the relationship between the expression of stem cell marker CD166 in colorectal cancer by immunohistochemistry and clinicopathologic parameters.Methods: From 2006 to 2012, 121 colectomy specimens of patients with colon cancer that were operated in Babol...

متن کامل

Clinicopathologic features and molecular subtypes of breast cancer in young women (age ≤35).

INTRODUCTION Breast cancer in young women is a relatively rare disease; however it tends to be more aggressive and is the leading cause of cancer death in this population. The aim of this study is to investigate the clinical and biological features of breast cancer arising in young Turkish breast cancer patients. MATERIALS AND METHODS Patients with breast cancer aged 35 or less (≤35 years) we...

متن کامل

Breast Cancer Molecular Subtypes Defined by ER/PR and HER2 Status: Association with Clinicopathologic Parameters in Ivorian Patients.

BACKGROUND Breast cancer is a heterogeneous disease that represents a major public health problem. The immunohistochemical determination of breast cancer subtypes with regard to estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor (HER2) status can contribute to improved selection of therapy and patientcare. The purpose of this study was to determine th...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Smart medical journal

سال: 2022

ISSN: ['2621-0916', '2621-1408']

DOI: https://doi.org/10.13057/smj.v5i2.59179